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Allosteric regulation in NMDA receptors revealed by the genetically encoded photo-cross-linkers
Allostery is essential to neuronal receptor function, but its transient nature poses a challenge for characterization. The N-terminal domains (NTDs) distinct from ligand binding domains are a major locus for allosteric regulation of NMDA receptors (NMDARs), where different modulatory binding sites h...
Autores principales: | Tian, Meilin, Ye, Shixin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054432/ https://www.ncbi.nlm.nih.gov/pubmed/27713495 http://dx.doi.org/10.1038/srep34751 |
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