Distinct Contributions of Replication and Transcription to Mutation Rate Variation of Human Genomes

Here, we evaluate the contribution of two major biological processes—DNA replication and transcription—to mutation rate variation in human genomes. Based on analysis of the public human tissue transcriptomics data, high-resolution replicating map of Hela cells and dbSNP data, we present significant...

Descripción completa

Detalles Bibliográficos
Autores principales: Cui, Peng, Ding, Feng, Lin, Qiang, Zhang, Lingfang, Li, Ang, Zhang, Zhang, Hu, Songnian, Yu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054443/
https://www.ncbi.nlm.nih.gov/pubmed/22449396
http://dx.doi.org/10.1016/S1672-0229(11)60028-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054443/
https://www.ncbi.nlm.nih.gov/pubmed/22449396
http://dx.doi.org/10.1016/S1672-0229(11)60028-4

Ejemplares similares