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In vivo functional and molecular characterization of the Penicillin-Binding Protein 4 (DacB) of Pseudomonas aeruginosa

BACKGROUND: Community and nosocomial infections by Pseudomonas aeruginosa still create a major therapeutic challenge. The resistance of this opportunist pathogen to β-lactam antibiotics is determined mainly by production of the inactivating enzyme AmpC, a class C cephalosporinase with a regulation s...

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Detalles Bibliográficos
Autores principales: Aguilera Rossi, Cristian Gustavo, Gómez-Puertas, Paulino, Ayala Serrano, Juan Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054556/
https://www.ncbi.nlm.nih.gov/pubmed/27716106
http://dx.doi.org/10.1186/s12866-016-0853-x