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Perip7lakin is a target for autoimmunity in asthma

The role of autoimmunity targeting epithelial antigens in asthma has been suggested, in particular in non-atopic and severe asthma. Periplakin, a desmosomal component, is involved in epithelial cohesion and intracellular signaling. We detected anti-periplakin IgG antibodies in 47/260 (18 %) patients...

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Detalles Bibliográficos
Autores principales: Taillé, Camille, Grootenboer-Mignot, Sabine, Estellat, Candice, Roy, Carine, Ly Ka So, Sophie, Pretolani, Marina, Aubier, Michel, Crestani, Bruno, Chollet-Martin, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054582/
https://www.ncbi.nlm.nih.gov/pubmed/27717390
http://dx.doi.org/10.1186/s12931-016-0441-5