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Picodroplet partitioned whole genome amplification of low biomass samples preserves genomic diversity for metagenomic analysis

BACKGROUND: Whole genome amplification (WGA) is a challenging, key step in metagenomic studies of samples containing minute amounts of DNA, such as samples from low biomass environments. It is well known that multiple displacement amplification (MDA), the most commonly used WGA method for microbial...

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Detalles Bibliográficos
Autores principales: Hammond, Maria, Homa, Felix, Andersson-Svahn, Helene, Ettema, Thijs J. G., Joensson, Haakan N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054601/
https://www.ncbi.nlm.nih.gov/pubmed/27716450
http://dx.doi.org/10.1186/s40168-016-0197-7