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Picodroplet partitioned whole genome amplification of low biomass samples preserves genomic diversity for metagenomic analysis
BACKGROUND: Whole genome amplification (WGA) is a challenging, key step in metagenomic studies of samples containing minute amounts of DNA, such as samples from low biomass environments. It is well known that multiple displacement amplification (MDA), the most commonly used WGA method for microbial...
Autores principales: | Hammond, Maria, Homa, Felix, Andersson-Svahn, Helene, Ettema, Thijs J. G., Joensson, Haakan N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054601/ https://www.ncbi.nlm.nih.gov/pubmed/27716450 http://dx.doi.org/10.1186/s40168-016-0197-7 |
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