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Selective depletion of tumour suppressors Deleted in Colorectal Cancer (DCC) and neogenin by environmental and endogenous serine proteases: linking diet and cancer

BACKGROUND: The related tumour suppressor proteins Deleted in Colorectal Cancer (DCC) and neogenin are absent or weakly expressed in many cancers, whereas their insertion into cells suppresses oncogenic behaviour. Serine proteases influence the initiation and progression of cancers although the mech...

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Detalles Bibliográficos
Autores principales: Forrest, Caroline M., McNair, Kara, Vincenten, Maria C. J., Darlington, L. Gail, Stone, Trevor W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054602/
https://www.ncbi.nlm.nih.gov/pubmed/27716118
http://dx.doi.org/10.1186/s12885-016-2795-y