PAK1 confers chemoresistance and poor outcome in non-small cell lung cancer via β-catenin-mediated stemness

PAK1 confers resistance to the estrogen antagonist tamoxifen in breast cancer. However, a role for PAK1 remains to be elucidated for chemoresistance and prognosis in non-small cell lung cancer (NSCLC). We provide evidence that PAK1 confers cisplatin resistance by increasing β-catenin expression thro...

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Detalles Bibliográficos
Autores principales: Chen, Ming-Jenn, Wu, De-Wei, Wang, Yao-Chen, Chen, Chi-Yi, Lee, Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054675/
https://www.ncbi.nlm.nih.gov/pubmed/27713506
http://dx.doi.org/10.1038/srep34933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054675/
https://www.ncbi.nlm.nih.gov/pubmed/27713506
http://dx.doi.org/10.1038/srep34933

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