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Cell surface GRP78 as a biomarker and target for suppressing glioma cells

High-grade glioma is a highly malignant and metastatic brain cancer, resistant to many existing anticancer treatments. In such glioma cancer cells, the glucose-regulated protein 78 kDa (GRP78) is particularly highly up-regulated. Former studies have thus targeted mutation-free GRP78 not only to dete...

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Detalles Bibliográficos
Autores principales: Kang, Bo Ram, Yang, Seung-Hoon, Chung, Bo-Ryehn, Kim, Woong, Kim, YoungSoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054676/
https://www.ncbi.nlm.nih.gov/pubmed/27713511
http://dx.doi.org/10.1038/srep34922