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Loss of Axin2 Causes Ocular Defects During Mouse Eye Development
PURPOSE: The scaffold protein Axin2 is an antagonist and universal target of the Wnt/β-catenin pathway. Disruption of Axin2 may lead to developmental eye defects; however, this has not been examined. The purpose of this study was to investigate the role of Axin2 during ocular and extraocular develop...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Association for Research in Vision and Ophthalmology
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054732/ https://www.ncbi.nlm.nih.gov/pubmed/27701636 http://dx.doi.org/10.1167/iovs.15-18599 |