BAC transgenic zebrafish reveal hypothalamic enhancer activity around obesity associated SNP rs9939609 within the human FTO gene

Single Nucleotide Polymorphisms in FTO intron 1 have been associated with obesity risk, leading to the hypothesis that FTO is the obesity‐related gene. However, other studies have shown that the FTO gene is part of the regulatory domain of the neighboring IRX3 gene and that enhancers in FTO intron 1...

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Detalles Bibliográficos
Autores principales: Rinkwitz, Silke, Geng, Fan‐Suo, Manning, Elizabeth, Suster, Maximiliano, Kawakami, Koichi, Becker, Thomas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054831/
https://www.ncbi.nlm.nih.gov/pubmed/26271004
http://dx.doi.org/10.1002/dvg.22884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054831/
https://www.ncbi.nlm.nih.gov/pubmed/26271004
http://dx.doi.org/10.1002/dvg.22884

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