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RNA‐Seq Reveals Acute Manganese Exposure Increases Endoplasmic Reticulum Related and Lipocalin mRNAs in Caenorhabditis elegans

Manganese (Mn) is an essential nutrient; nonetheless, excessive amounts can accumulate in brain tissues causing manganism, a severe neurological condition. Previous studies have suggested oxidative stress, mitochondria dysfunction, and impaired metabolism pathways as routes for Mn toxicity. Here, we...

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Detalles Bibliográficos
Autores principales: Rudgalvyte, Martina, Peltonen, Juhani, Lakso, Merja, Nass, Richard, Wong, Garry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054866/
https://www.ncbi.nlm.nih.gov/pubmed/26418576
http://dx.doi.org/10.1002/jbt.21768