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Different combinations of atomic interactions predict protein‐small molecule and protein‐DNA/RNA affinities with similar accuracy
Interactions between proteins and other molecules play essential roles in all biological processes. Although it is widely held that a protein's ligand specificity is determined primarily by its three‐dimensional structure, the general principles by which structure determines ligand binding rema...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054890/ https://www.ncbi.nlm.nih.gov/pubmed/26370248 http://dx.doi.org/10.1002/prot.24928 |