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The value of patient selection in demonstrating treatment effect in stroke recovery trials: lessons from the CHIMES study of MLC601 (NeuroAiD)

OBJECTIVE: The CHIMES Study compared MLC601 to placebo in patients with ischemic stroke of intermediate severity in the preceding 72 hours. We aimed to verify if patient selection based on two prognostic factors (ie, stroke severity and time to treatment) improves detection of a treatment effect wit...

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Detalles Bibliográficos
Autores principales: Venketasubramanian, Narayanaswamy, Lee, Chun Fan, Wong, K. S. Lawrence, Chen, Christopher L. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054909/
https://www.ncbi.nlm.nih.gov/pubmed/26291445
http://dx.doi.org/10.1111/jebm.12170