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The value of patient selection in demonstrating treatment effect in stroke recovery trials: lessons from the CHIMES study of MLC601 (NeuroAiD)
OBJECTIVE: The CHIMES Study compared MLC601 to placebo in patients with ischemic stroke of intermediate severity in the preceding 72 hours. We aimed to verify if patient selection based on two prognostic factors (ie, stroke severity and time to treatment) improves detection of a treatment effect wit...
Autores principales: | Venketasubramanian, Narayanaswamy, Lee, Chun Fan, Wong, K. S. Lawrence, Chen, Christopher L. H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054909/ https://www.ncbi.nlm.nih.gov/pubmed/26291445 http://dx.doi.org/10.1111/jebm.12170 |
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