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Defining antigen-specific plasmablast and memory B cell subsets in blood following viral infection and vaccination of humans

Antigen-specific B cells bifurcate into antibody secreting cells (ASC) and memory B cells after infection or vaccination. ASCs or plasmablasts have been extensively studied in humans but less is known about B cells that get activated but do not differentiate into early plasmablasts. Here, we define...

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Detalles Bibliográficos
Autores principales: Ellebedy, Ali H., Jackson, Katherine J.L., Kissick, Haydn T., Nakaya, Helder I., Davis, Carl W., Roskin, Krishna M., McElroy, Anita K., Oshansky, Christine M., Elbein, Rivka, Thomas, Shine, Lyon, George M., Spiropoulou, Christina F., Mehta, Aneesh K., Thomas, Paul G., Boyd, Scott D., Ahmed, Rafi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054979/
https://www.ncbi.nlm.nih.gov/pubmed/27525369
http://dx.doi.org/10.1038/ni.3533