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The importance of evolutionarily conserved C‐terminal basic residues for the stability of proapoptotic Bax protein

Bax is a protein that promotes apoptosis (a form of cell death). The atomistic details of the mechanism by which Bax is activated during apoptosis remain a subject of debate. C‐terminal basic residues in the sequence of Bax show remarkable conservation across a variety of species. The role of these...

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Detalles Bibliográficos
Autor principal: Rosas‐Trigueros, Jorge L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055034/
https://www.ncbi.nlm.nih.gov/pubmed/27761357
http://dx.doi.org/10.1002/2211-5463.12096