Stabilization of tryptophan hydroxylase 2 by l‐phenylalanine‐induced dimerization

Tryptophan hydroxylase 2 (TPH2) catalyses the initial and rate‐limiting step in the biosynthesis of serotonin, which is associated with a variety of disorders such as depression, obsessive compulsive disorder, and schizophrenia. Full‐length TPH2 is poorly characterized due to low purification quanti...

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Detalles Bibliográficos
Autores principales: Tidemand, Kasper D., Christensen, Hans E. M., Hoeck, Niclas, Harris, Pernille, Boesen, Jane, Peters, Günther H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055035/
https://www.ncbi.nlm.nih.gov/pubmed/27761358
http://dx.doi.org/10.1002/2211-5463.12100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055035/
https://www.ncbi.nlm.nih.gov/pubmed/27761358
http://dx.doi.org/10.1002/2211-5463.12100

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