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Ezetimibe reduced hepatic steatosis induced by dietary oxysterols in nonhuman primates

Oxidized cholesterol (oxysterols) plays an important and multifaceted role in lipid metabolism. Here we examined whether dietary oxysterols accelerate hepatic lipid accumulation and inflammation in nonhuman primates. We also examined the effect of the Niemann–Pick C1‐like1 inhibitor, ezetimibe (Ez)....

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Detalles Bibliográficos
Autores principales: Deushi, Michiyo, Osaka, Mizuko, Nakano, Kaku, Osada, Kyoichi, Egashira, Kensuke, Yoshida, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055037/
https://www.ncbi.nlm.nih.gov/pubmed/27761360
http://dx.doi.org/10.1002/2211-5463.12107