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Neural Stem Cell Tumorigenicity and Biodistribution Assessment for Phase I Clinical Trial in Parkinson’s Disease

Human pluripotent stem cells (PSC) have the potential to revolutionize regenerative medicine. However undifferentiated PSC can form tumors and strict quality control measures and safety studies must be conducted before clinical translation. Here we describe preclinical tumorigenicity and biodistribu...

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Detalles Bibliográficos
Autores principales: Garitaonandia, Ibon, Gonzalez, Rodolfo, Christiansen-Weber, Trudy, Abramihina, Tatiana, Poustovoitov, Maxim, Noskov, Alexander, Sherman, Glenn, Semechkin, Andrey, Snyder, Evan, Kern, Russell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055076/
https://www.ncbi.nlm.nih.gov/pubmed/27686862
http://dx.doi.org/10.1038/srep34478