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Homology modeling, molecular dynamics, and virtual screening of NorA efflux pump inhibitors of Staphylococcus aureus

Emerging drug resistance in clinical isolates of Staphylococcus aureus might be implicated to the overexpression of NorA efflux pump which is capable of extruding numerous structurally diverse compounds. However, NorA efflux pump is considered as a potential drug target for the development of efflux...

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Detalles Bibliográficos
Autores principales: Bhaskar, Baki Vijaya, Babu, Tirumalasetty Muni Chandra, Reddy, Netala Vasudeva, Rajendra, Wudayagiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055111/
https://www.ncbi.nlm.nih.gov/pubmed/27757014
http://dx.doi.org/10.2147/DDDT.S113556