Rapid disintegrating tablets of simvastatin dispersions in polyoxyethylene–polypropylene block copolymer for maximized disintegration and dissolution

The objective of this research was to improve the dissolution of simvastatin and to incorporate it in rapid disintegrating tablets (RDTs) with an optimized disintegration and dissolution characteristics. Polyoxyethylene–polypropylene block copolymer (poloxamer 188) was employed as a hydrophilic carr...

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Detalles Bibliográficos
Autores principales: Balata, Gehan F, Zidan, Ahmad S, Abourehab, Mohamad AS, Essa, Ebtessam A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055116/
https://www.ncbi.nlm.nih.gov/pubmed/27757012
http://dx.doi.org/10.2147/DDDT.S114724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055116/
https://www.ncbi.nlm.nih.gov/pubmed/27757012
http://dx.doi.org/10.2147/DDDT.S114724

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