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Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells

Understanding human embryonic ventral midbrain is of major interest for Parkinson’s disease. However, the cell types, their gene expression dynamics, and their relationship to commonly used rodent models remain to be defined. We performed single-cell RNA sequencing to examine ventral midbrain develo...

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Detalles Bibliográficos
Autores principales: La Manno, Gioele, Gyllborg, Daniel, Codeluppi, Simone, Nishimura, Kaneyasu, Salto, Carmen, Zeisel, Amit, Borm, Lars E., Stott, Simon R.W., Toledo, Enrique M., Villaescusa, J. Carlos, Lönnerberg, Peter, Ryge, Jesper, Barker, Roger A., Arenas, Ernest, Linnarsson, Sten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055122/
https://www.ncbi.nlm.nih.gov/pubmed/27716510
http://dx.doi.org/10.1016/j.cell.2016.09.027