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Effect of connexin 43 inhibition by the mimetic peptide Gap27 on corneal wound healing, inflammation and neovascularization

BACKGROUND AND PURPOSE: The connexin 43 (Cx43) mimetic peptide Gap27 was designed to transiently block the function of this gap junction. This study was undertaken to investigate the effect of Gap27 on corneal healing, inflammation and neovascularization. EXPERIMENTAL APPROACH: The effect of Gap27 o...

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Detalles Bibliográficos
Autores principales: Elbadawy, Hossein Mostafa, Mirabelli, Pierfrancesco, Xeroudaki, Maria, Parekh, Mohit, Bertolin, Marina, Breda, Claudia, Cagini, Carlo, Ponzin, Diego, Lagali, Neil, Ferrari, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055138/
https://www.ncbi.nlm.nih.gov/pubmed/27472295
http://dx.doi.org/10.1111/bph.13568