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Targeted TET oxidase activity through methyl‐CpG‐binding domain extensively suppresses cancer cell proliferation
DNA methyltransferase (DNMT) inhibitors are epigenetic drugs used to treat myelodysplastic syndrome. They not only induce DNA demethylation but also have significant cytostatic and cytotoxic effects; however, the relationships between these characteristics have not been established yet due to the la...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055179/ https://www.ncbi.nlm.nih.gov/pubmed/27457352 http://dx.doi.org/10.1002/cam4.830 |