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Targeted TET oxidase activity through methyl‐CpG‐binding domain extensively suppresses cancer cell proliferation

DNA methyltransferase (DNMT) inhibitors are epigenetic drugs used to treat myelodysplastic syndrome. They not only induce DNA demethylation but also have significant cytostatic and cytotoxic effects; however, the relationships between these characteristics have not been established yet due to the la...

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Detalles Bibliográficos
Autores principales:	Mizuguchi, Yasuhiko, Saiki, Yuriko, Horii, Akira, Fukushige, Shinichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055179/ https://www.ncbi.nlm.nih.gov/pubmed/27457352 http://dx.doi.org/10.1002/cam4.830

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