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A novel hedgehog inhibitor iG2 suppresses tumorigenesis by impairing self‐renewal in human bladder cancer

Tumor recurrence is still a major challenge for clinical treatment of bladder cancer. Cumulative evidences indicate cancer stem cells (CSCs) contribute to drug resistance and leave a putative source for disease relapse. Identifying novel agents targeting CSCs may represent a new paradigm in the ther...

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Detalles Bibliográficos
Autores principales: Zhu, Lihong, Ni, Chen, Dong, Baijun, Zhang, Yong, Shi, Yuefeng, Niu, Haitao, Li, Chong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055183/
https://www.ncbi.nlm.nih.gov/pubmed/27465044
http://dx.doi.org/10.1002/cam4.802