RUNX1 truncation resulting from a cryptic and novel t(6;21)(q25;q22) chromosome translocation in acute myeloid leukemia: A case report

Fluorescence in situ hybridization examination of a pediatric AML patient whose bone marrow cells carried trisomy 4 and FLT3-ITD mutation, demonstrated that part of the RUNX1 probe had unexpectedly moved to chromosome band 6q25 indicating a cryptic t(6;21)(q25;q22) translocation. RNA sequencing show...

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Detalles Bibliográficos
Autores principales: Panagopoulos, Ioannis, Torkildsen, Synne, Gorunova, Ludmila, Ulvmoen, Aina, Tierens, Anne, Zeller, Bernward, Heim, Sverre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055202/
https://www.ncbi.nlm.nih.gov/pubmed/27667292
http://dx.doi.org/10.3892/or.2016.5119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055202/
https://www.ncbi.nlm.nih.gov/pubmed/27667292
http://dx.doi.org/10.3892/or.2016.5119

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