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RUNX1 truncation resulting from a cryptic and novel t(6;21)(q25;q22) chromosome translocation in acute myeloid leukemia: A case report
Fluorescence in situ hybridization examination of a pediatric AML patient whose bone marrow cells carried trisomy 4 and FLT3-ITD mutation, demonstrated that part of the RUNX1 probe had unexpectedly moved to chromosome band 6q25 indicating a cryptic t(6;21)(q25;q22) translocation. RNA sequencing show...
Autores principales: | Panagopoulos, Ioannis, Torkildsen, Synne, Gorunova, Ludmila, Ulvmoen, Aina, Tierens, Anne, Zeller, Bernward, Heim, Sverre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055202/ https://www.ncbi.nlm.nih.gov/pubmed/27667292 http://dx.doi.org/10.3892/or.2016.5119 |
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