Identification and Tumour-Binding Properties of a Peptide with High Affinity to the Disialoganglioside GD2

Neuroectodermal tumours are characterized by aberrant processing of disialogangliosides concomitant with high expression of GD2 or GD3 on cell surfaces. Antibodies targeting GD2 are already in clinical use for therapy of neuroblastoma, a solid tumour of early childhood. Here, we set out to identify...

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Detalles Bibliográficos
Autores principales: Müller, Jan, Reichel, Robin, Vogt, Sebastian, Müller, Stefan P., Sauerwein, Wolfgang, Brandau, Wolfgang, Eggert, Angelika, Schramm, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055303/
https://www.ncbi.nlm.nih.gov/pubmed/27716771
http://dx.doi.org/10.1371/journal.pone.0163648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055303/
https://www.ncbi.nlm.nih.gov/pubmed/27716771
http://dx.doi.org/10.1371/journal.pone.0163648

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