Gdown1 Associates Efficiently with RNA Polymerase II after Promoter Clearance and Displaces TFIIF during Transcript Elongation

Pausing during the earliest stage of transcript elongation by RNA polymerase II (Pol II) is a nearly universal control point in metazoan gene expression. The substoichiometric Pol II subunit Gdown1 facilitates promoter proximal pausing in vitro in extract-based transcription reactions, out-competes...

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Detalles Bibliográficos
Autores principales: DeLaney, Elizabeth, Luse, Donal S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055313/
https://www.ncbi.nlm.nih.gov/pubmed/27716820
http://dx.doi.org/10.1371/journal.pone.0163649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055313/
https://www.ncbi.nlm.nih.gov/pubmed/27716820
http://dx.doi.org/10.1371/journal.pone.0163649

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