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Mechano-chemical Interactions in Cardiac Sarcomere Contraction: A Computational Modeling Study
We developed a model of cardiac sarcomere contraction to study the calcium-tension relationship in cardiac muscle. Calcium mediates cardiac contraction through its interactions with troponin (Tn) and subsequently tropomyosin molecules. Experimental studies have shown that a slight increase in intrac...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055322/ https://www.ncbi.nlm.nih.gov/pubmed/27716775 http://dx.doi.org/10.1371/journal.pcbi.1005126 |