Cargando…
Mechano-chemical Interactions in Cardiac Sarcomere Contraction: A Computational Modeling Study
We developed a model of cardiac sarcomere contraction to study the calcium-tension relationship in cardiac muscle. Calcium mediates cardiac contraction through its interactions with troponin (Tn) and subsequently tropomyosin molecules. Experimental studies have shown that a slight increase in intrac...
Autores principales: | Dupuis, Lauren J., Lumens, Joost, Arts, Theo, Delhaas, Tammo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055322/ https://www.ncbi.nlm.nih.gov/pubmed/27716775 http://dx.doi.org/10.1371/journal.pcbi.1005126 |
Ejemplares similares
-
High tension in sarcomeres hinders myocardial relaxation: A computational study
por: Dupuis, Lauren J., et al.
Publicado: (2018) -
Control of Whole Heart Geometry by Intramyocardial Mechano-Feedback: A Model Study
por: Arts, Theo, et al.
Publicado: (2012) -
A Closed-Loop Modeling Framework for Cardiac-to-Coronary Coupling
por: Munneke, Anneloes G., et al.
Publicado: (2022) -
Three-Wall Segment (TriSeg) Model Describing Mechanics and Hemodynamics of Ventricular Interaction
por: Lumens, Joost, et al.
Publicado: (2009) -
Myocardial perfusion and flow reserve in the asynchronous heart: mechanistic insight from a computational model
por: Munneke, Anneloes G., et al.
Publicado: (2023)