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Cathepsin L Helps to Defend Mice from Infection with Influenza A

Host-derived proteases can augment or help to clear infections. This dichotomy is exemplified by cathepsin L (CTSL), which helps Hendra virus and SARS coronavirus to invade cells, but is essential for survival in mice with mycoplasma pneumonia. The present study tested the hypothesis that CTSL prote...

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Detalles Bibliográficos
Autores principales: Xu, Xiang, Greenland, John R., Gotts, Jeffrey E., Matthay, Michael A., Caughey, George H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055332/
https://www.ncbi.nlm.nih.gov/pubmed/27716790
http://dx.doi.org/10.1371/journal.pone.0164501