MicroNeurotrophins Improve Survival in Motor Neuron-Astrocyte Co-Cultures but Do Not Improve Disease Phenotypes in a Mutant SOD1 Mouse Model of Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease caused by loss of motor neurons. ALS patients experience rapid deterioration in muscle function with an average lifespan of 3–5 years after diagnosis. Currently, the most effective therapeutic only extends lifespan by a few months, t...

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Detalles Bibliográficos
Autores principales: Glajch, Kelly E., Ferraiuolo, Laura, Mueller, Kaly A., Stopford, Matthew J., Prabhkar, Varsha, Gravanis, Achille, Shaw, Pamela J., Sadri-Vakili, Ghazaleh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055348/
https://www.ncbi.nlm.nih.gov/pubmed/27716798
http://dx.doi.org/10.1371/journal.pone.0164103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055348/
https://www.ncbi.nlm.nih.gov/pubmed/27716798
http://dx.doi.org/10.1371/journal.pone.0164103

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