Increased CD40 Expression Enhances Early STING-Mediated Type I Interferon Response and Host Survival in a Rodent Malaria Model

Both type I interferon (IFN-I) and CD40 play a significant role in various infectious diseases, including malaria and autoimmune disorders. CD40 is mostly known to function in adaptive immunity, but previous observations of elevated CD40 levels early after malaria infection of mice led us to investi...

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Detalles Bibliográficos
Autores principales: Yao, Xiangyu, Wu, Jian, Lin, Meng, Sun, Wenxiang, He, Xiao, Gowda, Channe, Bolland, Silvia, Long, Carole A., Wang, Rongfu, Su, Xin-zhuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055354/
https://www.ncbi.nlm.nih.gov/pubmed/27716849
http://dx.doi.org/10.1371/journal.ppat.1005930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055354/
https://www.ncbi.nlm.nih.gov/pubmed/27716849
http://dx.doi.org/10.1371/journal.ppat.1005930

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