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Maintenance of leukemic cell identity by the activity of the Polycomb complex PRC1 in mice
Leukemia is a complex heterogeneous disease often driven by the expression of oncogenic fusion proteins with different molecular and biochemical properties. Whereas several fusion proteins induce leukemogenesis by activating Hox gene expression (Hox-activating fusions), others impinge on different p...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055382/ https://www.ncbi.nlm.nih.gov/pubmed/27730210 http://dx.doi.org/10.1126/sciadv.1600972 |