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Maintenance of leukemic cell identity by the activity of the Polycomb complex PRC1 in mice

Leukemia is a complex heterogeneous disease often driven by the expression of oncogenic fusion proteins with different molecular and biochemical properties. Whereas several fusion proteins induce leukemogenesis by activating Hox gene expression (Hox-activating fusions), others impinge on different p...

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Detalles Bibliográficos
Autores principales: Rossi, Alessandra, Ferrari, Karin J., Piunti, Andrea, Jammula, SriGanesh, Chiacchiera, Fulvio, Mazzarella, Luca, Scelfo, Andrea, Pelicci, Pier Giuseppe, Pasini, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055382/
https://www.ncbi.nlm.nih.gov/pubmed/27730210
http://dx.doi.org/10.1126/sciadv.1600972