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Direct Sensing of Nutrients via a LAT1-like Transporter in Drosophila Insulin-Producing Cells

Dietary leucine has been suspected to play an important role in insulin release, a hormone that controls satiety and metabolism. The mechanism by which insulin-producing cells (IPCs) sense leucine and regulate insulin secretion is still poorly understood. In Drosophila, insulin-like peptides (DILP2...

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Detalles Bibliográficos
Autores principales: Manière, Gérard, Ziegler, Anna B., Geillon, Flore, Featherstone, David E., Grosjean, Yael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055474/
https://www.ncbi.nlm.nih.gov/pubmed/27681427
http://dx.doi.org/10.1016/j.celrep.2016.08.093