MERVL/Zscan4 Network Activation Results in Transient Genome-wide DNA Demethylation of mESCs

Mouse embryonic stem cells are dynamic and heterogeneous. For example, rare cells cycle through a state characterized by decondensed chromatin and expression of transcripts, including the Zscan4 cluster and MERVL endogenous retrovirus, which are usually restricted to preimplantation embryos. Here, w...

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Detalles Bibliográficos
Autores principales: Eckersley-Maslin, Mélanie A., Svensson, Valentine, Krueger, Christel, Stubbs, Thomas M., Giehr, Pascal, Krueger, Felix, Miragaia, Ricardo J., Kyriakopoulos, Charalampos, Berrens, Rebecca V., Milagre, Inês, Walter, Jörn, Teichmann, Sarah A., Reik, Wolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055476/
https://www.ncbi.nlm.nih.gov/pubmed/27681430
http://dx.doi.org/10.1016/j.celrep.2016.08.087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055476/
https://www.ncbi.nlm.nih.gov/pubmed/27681430
http://dx.doi.org/10.1016/j.celrep.2016.08.087

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