Exogenous Administration of Recombinant MIF at Physiological Concentrations Failed to Attenuate Infarct Size in a Langendorff Perfused Isolated Mouse Heart Model

PURPOSE: Evidence suggests a two-pronged role of endogenous macrophage migration inhibitory factor (MIF) release in ischemia/reperfusion injury. We aimed to assess whether its exogenous administration confers cardioprotection. METHODS: Male C57/BL6 mice were randomly allocated to receive recombinant...

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Detalles Bibliográficos
Autores principales: Rossello, Xavier, Burke, Niall, Stoppe, Christian, Bernhagen, Jurgen, Davidson, Sean M., Yellon, Derek M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055564/
https://www.ncbi.nlm.nih.gov/pubmed/27335054
http://dx.doi.org/10.1007/s10557-016-6673-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055564/
https://www.ncbi.nlm.nih.gov/pubmed/27335054
http://dx.doi.org/10.1007/s10557-016-6673-2

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