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The Coordinated Positive Regulation of Topoisomerase Genes Maintains Topological Homeostasis in Streptomyces coelicolor

Maintaining an optimal level of chromosomal supercoiling is critical for the progression of DNA replication and transcription. Moreover, changes in global supercoiling affect the expression of a large number of genes and play a fundamental role in adapting to stress. Topoisomerase I (TopA) and gyras...

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Detalles Bibliográficos
Autores principales: Szafran, Marcin Jan, Gongerowska, Martyna, Gutkowski, Paweł, Zakrzewska-Czerwińska, Jolanta, Jakimowicz, Dagmara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055605/
https://www.ncbi.nlm.nih.gov/pubmed/27551021
http://dx.doi.org/10.1128/JB.00530-16