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Barriers to the Preclinical Development of Therapeutics that Target Aging Mechanisms

Through the progress of basic science research, fundamental mechanisms that contribute to age-related decline are being described with increasing depth and detail. Although these efforts have identified new drug targets and compounds that extend life span in model organisms, clinical trials of thera...

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Detalles Bibliográficos
Autores principales: Burd, Christin E., Gill, Matthew S., Niedernhofer, Laura J., Robbins, Paul D., Austad, Steven N., Barzilai, Nir, Kirkland, James L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055650/
https://www.ncbi.nlm.nih.gov/pubmed/27535964
http://dx.doi.org/10.1093/gerona/glw112