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Does conservation account for splicing patterns?

BACKGROUND: Alternative mRNA splicing is critical to proteomic diversity and tissue and species differentiation. Exclusion of cassette exons, also called exon skipping, is the most common type of alternative splicing in mammals. RESULTS: We present a computational model that predicts absolute (thoug...

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Detalles Bibliográficos
Autores principales: Wainberg, Michael, Alipanahi, Babak, Frey, Brendan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055659/
https://www.ncbi.nlm.nih.gov/pubmed/27717327
http://dx.doi.org/10.1186/s12864-016-3121-4