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Discovery of immunodominant T-cell epitopes reveals penton protein as a second immunodominant target in human adenovirus infection
BACKGROUND: Human adenovirus (HAdV) infections remain a significant cause of morbidity and mortality after hematopoietic stem cell transplantation (HSCT). Efficient antiviral T-cell responses are necessary to clear infection, which is hampered by delayed immune reconstitution and medical immunosuppr...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055684/ https://www.ncbi.nlm.nih.gov/pubmed/27717382 http://dx.doi.org/10.1186/s12967-016-1042-2 |