Biophysical Determinants for Cellular Uptake of Hydrocarbon-Stapled Peptide Helices

Hydrocarbon-stapled peptides are a class of bioactive alpha-helical ligands developed to dissect and target protein interactions. While there is consensus that stapled peptides can be effective chemical tools for investigating protein regulation, their broader utility for therapeutic modulation of i...

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Detalles Bibliográficos
Autores principales: Bird, Gregory H., Mazzola, Emanuele, Opoku-Nsiah, Kwadwo, Lammert, Margaret A., Godes, Marina, Neuberg, Donna S., Walensky, Loren D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055751/
https://www.ncbi.nlm.nih.gov/pubmed/27547919
http://dx.doi.org/10.1038/nchembio.2153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055751/
https://www.ncbi.nlm.nih.gov/pubmed/27547919
http://dx.doi.org/10.1038/nchembio.2153

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