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Activating and Attenuating the Amicoumacin Antibiotics

The amicoumacins belong to a class of dihydroisocoumarin natural products and display antibacterial, antifungal, anticancer, and anti-inflammatory activities. Amicoumacins are the pro-drug activation products of a bacterial nonribosomal peptide-polyketide hybrid biosynthetic pathway and have been is...

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Detalles Bibliográficos
Autores principales: Park, Hyun Bong, Perez, Corey E., Perry, Elena Kim, Crawford, Jason M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055758/
https://www.ncbi.nlm.nih.gov/pubmed/27347911
http://dx.doi.org/10.3390/molecules21070824