C3a Increases VEGF and Decreases PEDF mRNA Levels in Human Retinal Pigment Epithelial Cells

Complement activation, specifically complement 3 (C3) activation and C3a generation, contributes to an imbalance between angiogenic stimulation by vascular endothelial growth factor (VEGF) and angiogenic inhibition by pigment epithelial derived factor (PEDF), leading to pathological angiogenesis. Th...

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Detalles Bibliográficos
Autores principales: Long, Qin, Cao, Xiaoguang, Bian, Ailing, Li, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055919/
https://www.ncbi.nlm.nih.gov/pubmed/27747237
http://dx.doi.org/10.1155/2016/6958752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055919/
https://www.ncbi.nlm.nih.gov/pubmed/27747237
http://dx.doi.org/10.1155/2016/6958752

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