Disproportionately Elevated Proinsulin Levels as an Early Indicator of β-Cell Dysfunction in Nondiabetic Offspring of Chinese Diabetic Patients

Objective. To study the characteristics of β-cell dysfunction and insulin resistance (IR) in the first-degree relatives (FDRs) of T2DM in Chinese population and to examine the usefulness of proinsulin (PI) for evaluating β-cell dysfunction. Methods. 229 subjects of nondiabetic FDRs, 71 newly diagnos...

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Detalles Bibliográficos
Autores principales: Li, Ming, Feng, Dan, Zhang, Kui, Gao, Shan, Lu, Juming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055967/
https://www.ncbi.nlm.nih.gov/pubmed/27746815
http://dx.doi.org/10.1155/2016/4740678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055967/
https://www.ncbi.nlm.nih.gov/pubmed/27746815
http://dx.doi.org/10.1155/2016/4740678

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