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Altered Left Ventricular Ion Channel Transcriptome in a High-Fat-Fed Rat Model of Obesity: Insight into Obesity-Induced Arrhythmogenesis

Introduction. Obesity is increasingly common and is associated with an increased prevalence of cardiac arrhythmias. The aim of this study was to see whether in obesity there is proarrhythmic gene expression of ventricular ion channels and related molecules. Methods and Results. Rats were fed on a hi...

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Detalles Bibliográficos
Autores principales: Ashrafi, Reza, Yon, Marianne, Pickavance, Lucy, Yanni Gerges, Joseph, Davis, Gershan, Wilding, John, Jian, Kun, Zhang, Henggui, Hart, George, Boyett, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056006/
https://www.ncbi.nlm.nih.gov/pubmed/27747100
http://dx.doi.org/10.1155/2016/7127898