Activation of Human Complement System by Dextran-Coated Iron Oxide Nanoparticles Is Not Affected by Dextran/Fe Ratio, Hydroxyl Modifications, and Crosslinking

While having tremendous potential as therapeutic and imaging tools, the clinical use of engineered nanoparticles has been associated with serious safety concerns. Activation of the complement cascade and the release of proinflammatory factors C3a and C5a may contribute to infusion-related reactions,...

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Detalles Bibliográficos
Autores principales: Wang, Guankui, Chen, Fangfang, Banda, Nirmal K., Holers, V. Michael, Wu, LinPing, Moghimi, S. Moein, Simberg, Dmitri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056169/
https://www.ncbi.nlm.nih.gov/pubmed/27777575
http://dx.doi.org/10.3389/fimmu.2016.00418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056169/
https://www.ncbi.nlm.nih.gov/pubmed/27777575
http://dx.doi.org/10.3389/fimmu.2016.00418

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